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Participants on the highest dose (15 mg) achieved an average weight reduction of 22.9% over three years, marking one of the longest documented sustained weight loss effects in obesity pharmacotherapy
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
These categories differ in the magnitude and direction of receptor activation, enabling tailored therapeutic applications depending on disease mechanisms and required biological responses
715-725.e3, Apr
