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Melatonin receptors: molecular pharmacology and signalling in the context of system bias
Cardio- and reno-protective effects are unlikely to be solely explained by the mechanisms used by these drugs to lower blood glucose levels, as the same effects are not seen with drugs that have stronger antihyperglycaemic actions [111], and were not dependent upon the degree of HbA1c reduction [113,114,115]
Other notable side effects included fatigue, joint pain, hair loss, and headaches, particularly with drugs such as tirzepatide
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