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Cytotoxic CD8+ T cells serve as the primary effectors of antitumor immunity (93,94)
The enhanced efficacy of tirzepatide likely stems from its dual mechanism: The addition of GIP receptor activation appears to provide synergistic benefits, potentially through: Enhanced insulin secretion Direct effects on adipose tissue Complementary appetite regulation pathways The Next Frontier: Triple Agonist Research If dual agonism improves upon single agonism, what about triple agonism
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