retatrutide peptide triple hormone receptor agonist Medscape | Retatrutide, Eli Lilly's first-in-class agonist, delivered meaningful weight loss at 80 weeks in all doses in the Achieve Your Weight Loss Goals

Here's what changed my mind

Miller-Materos large study confirms prior evidence, from Tufvesson-Alm and colleagues, regarding the role of the gutbrain axis in alcohol use

This can make it much easier to manage your appetite and reduce your overall calorie intake without feeling constantly hungry

7 Additionally, experimental evidence suggests that obesity-associated inflammatory changes in seminal plasma may influence the uterine immune environment after conception

Its the early testing edge that has Regeneron excited about Hansohs HS-20094, since the drug has already been studied in over 1k patients, leading Regeneron to claim it has a potentially similar profile to Lillys popular GLP-1/GIP agonist