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This reaction is critical for DNA synthesis, red blood cell formation, and nervous system function

Individuals with a personal history of depression, eating disorders, or poorly controlled type 2 diabetes may warrant closer mental health monitoring during treatment

C., Celsi, G

Additional comparative evidence comes from: A 2025 narrative review synthesising randomised and indirect comparison data across obesity and type 2 diabetes trials, confirming tirzepatides superiority on weight and HbA1c [2]

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