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Medication alone cannot overcome certain behavioral and environmental factors that influence metabolic health

Additional possible effects encompass indigestion, bloating, burping, gas, reflux, heartburn, fatigue, dizziness, low blood pressure, reduced appetite, hair loss, rapid pulse, and injection site reactions

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Other contributing factors include medication interactions (certain psychiatric medications, corticosteroids, and reduced exposure to oral contraceptives during dose escalation), hormonal changes (thyroid dysfunction, menopause), inadequate sleep (less than 7 hours nightly), chronic stress with elevated cortisol, and reduced physical activity as patients become more comfortable at their current weight