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Patient safety and product quality must remain the top priority, and FDA approval pathways play a critical role in ensuring clinical efficacy, proper dosing, and risk management

In closing, the story of cinnamon in metabolic disease exemplifies a broader principle: targeting membrane signaling, the interfaces through which cells perceive and react to their environment, can yield broad and favorable outcomes in complex diseases

Sacks, and Kosali I

Rather than a reason to panic, this finding should be seen as a reminder: no drug is without risk, but knowledge empowers both patients and providers to act quickly if needed

N Engl J Med 381(7):637646