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Tirzepatide effectively reduces body weight, but preserving muscle tissue requires intentional nutrition and exercise planning

These drugs often reduce appetite but can also cause muscle loss.
It has been thought that incretin signaling prevents arteriosclerosis, and very recently anti-arteriosclerotic effects through GLP-1 receptor were finally demonstrated in clinical human study

The diabetes drug Ozempic has seen supply chain issues due to off label prescribing for weight loss

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