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Future research should focus on prospective clinical trials to validate these findings, explore the underlying mechanisms and determine the long-term efficacy and safety of GIP/GLP-1 RA medications in diverse populations. Important as it is to accumulate more evidence for any hypothesis, these sorts of studies alone cant definitively prove that GLP-1 drugs should be added to the roster of medications for substance use disorder just yet
Heres why I still use it often in my practice at JourneyLite: 1
Yet by September 2023, the FDA required adding ileus warnings after post-marketing reports documented severe intestinal blockages
Exenatide (Byetta and Bydureon , AstraZeneca, Cambridge, UK), a synthetic 39-amino acid peptide that was the first GLP-1 RA approved for clinical use [25,59,60] or Lixisenatide (Sanofi, Paris, France), is an analog of exenatide, with comparable pharmacokinetic properties [25,61]
buccal, gingival, sublingual)] or rectal route
