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Nakatani Y, Maeda M, Matsumura M, et al
(2012) 59:A4519
The two types of incretin hormones that have critical roles in incretin signaling, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), bind to specific members of the G-protein-coupled receptor (GPCR) family: the GLP-1 receptor (GLP-1R) and the GIP receptor (GIPR), respectively
Mood Changes and Depression: Although some studies point to antidepressant effects, some individuals may experience negative mood changes, including the onset or worsening of depressive symptoms
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