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Description

Tirzepatide is the first combination of entero-pancreatic hormones [dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) RA] that has been approved for T2D management based on the findings from the phase 3 SURPASS programme

It it's it's cumulative movement and keeping your body you know, people have used the term keeping your sword sharp, and I love that term personally

However, I'm interested by some of the comments regarding receptor down regulation in the setting of a high dose drug administration

Retatrutide is a 39-amino-acid synthetic peptide with multiple non-natural modifications including Aib substitutions, an alpha-methyl leucine, and a C20 fatty diacid conjugation via a chemical linker