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Conclusions Modern antiobesity drugs have changed clinical care by making double-digit weight loss achievable for many patients
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Even the lowest tirzepatide dose (5 mg) outperformed semaglutide 1.0 mg for weight loss

This is exactly why controlled trials are needed and why microdosing should be approached with appropriate medical supervision, not self-experimented with based on internet articles alone

Use of fiber supplements can help manage constipation related to taking GLP-1s

Retatrutide is an investigational compound still in clinical development and is supplied strictly for laboratory research use only
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