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Impact of Semaglutide on High-Sensitivity C-Reactive Protein: Exploratory Patient-Level Analyses of SUSTAIN and PIONEER Trials

Human GLP1R variants affecting GLP1R cell surface expression contribute to impaired glucose control and increased adiposity

What the label actually says The Mounjaro and Zepbound prescribing information states: "Available data with tirzepatide use in pregnant women are insufficient to evaluate for a drug-related risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes." The label then references animal studies: "Based on animal reproduction studies, there may be risks to the fetus from exposure to tirzepatide during pregnancy." And the recommendation: "Advise pregnant women of the potential risk to a fetus

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Inclusion in the MDL does not establish that Trulicity caused any injury, but it reflects that plaintiffs are raising overlapping allegations across the GLP-1 drug category