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Both tirzepatide and semaglutide showed significant lean mass reduction alongside their stronger overall weight loss results
J Am Coll Cardiol 2024;84:1646-62.PubMed 98
Understanding the difference starts with understanding what incretin hormones are and why activating more than one receptor changes things
Some discussions also speculate about the way GLP-1based medicines affect appetite regulation, metabolism, and brain signalling
