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Description
Quick Answer: Tirzepatide does not require tapering from a pharmacological perspective, as the FDA prescribing information does not mandate gradual dose reduction when stopping treatment
GLP-1 receptor agonism in the area postrema and nucleus tractus solitarius drives the emetic response
[DOI] [PubMed] [Google Scholar] 32.Watson KT, Wroolie TE, Tong G, et al
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Thats a fundamentally different mechanism than anything currently on the market
