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This washout period helps ensure the drug is out of your system

Therefore, it is likely that a once-weekly fixed-ratio combination of basal insulin and GLP-1 RA could help mitigate the inertia often associated with insulin initiation and relieve the treatment burden of daily injections [7,8,9]

As mentioned above, a GLP-1 receptor agonist works by mimicking the natural incretin hormone (hormones secreted by the gut) GLP-1, which may assist in lowering blood sugar in the following ways 7 , 8 : Increase insulin when blood glucose (sugar) is high: They enhance the bodys ability to release insulin when blood sugar levels are elevated