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The adjusted difference in mean SBP (mm Hg) change between groups in participants with pre-existing hypertension was 11.6 mm Hg

In addition, not every patient requires the full therapeutic dose to achieve improvements in glucose control or weight reduction

These can include oral devices, nerve stimulators, surgical correction, lifestyle changes, positional aids, and in some cases, medication

Beyond the direct medication concerns, theres another fundamental issue
Most users adapt and find this shift helpful once they understand it's a temporary neurological adjustment, not a permanent change in their preferences