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Description
How semaglutide works Semaglutide is a selective GLP-1 receptor agonist

This is where most confusion starts, and where most dosing errors originate

The consistency of results across both diabetes and obesity populations suggests that dual agonism provides robust metabolic benefits that extend beyond glucose control to address the full spectrum of metabolic dysfunction

On October 2, 2024, the FDA declared the tirzepatide shortage resolved

The state of play in 2026 For years, clinicians compared tirzepatide and semaglutide across separate trials with different patient populations, different endpoints, and different study designs
