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GIP (142) Asp 21 may form a hydrogen bond with GIPR Arg 131 and the mutation of GIPR Arg 131 to Ala decreases the affinity and activity

Pandey A, Patel KV, Segar MW, Ayers C, Linge J, Leinhard OD, et al
doi: 10.1016/j.cmet.2016.08.020

doi:10.1210/er.2015-1084 9
