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Individuals with severe gastrointestinal problems such as gastroparesis (delayed stomach emptying) or a history of severe pancreatitis (inflammation of the pancreas) should not use tirzepatide, as it can aggravate these conditions

Women suffering from IIH have a BMI on average around 38 and IIH is not currently recognised as a co-morbidity for bariatric surgery

In my clinical experience, many patients who plateau on semaglutide see renewed progress after transitioning to tirzepatide, although individual results vary and treatment decisions should always be guided by a medical provider
The Obesity Medicine Association strongly recommends that individuals stop taking these medications before attempting to conceive