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Abstract Background In idiopathic intracranial hypertension (IIH), sustained weight loss is the main pillar in modifying disease course, whereby glucagon-like peptide-1 receptor agonists (GLP-1-RAs) could present an attractive treatment option

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In a phase II trial of subcutaneous semaglutide, rapid dose escalation led to greater weight loss but more adverse events

These may indicate nutrient deficiency, dehydration, or an individual intolerance requiring dose reduction or medication discontinuation

Our study covers a broad group of patients and provides strong support that GLP-1 analogues are not associated with an increased risk of thyroid cancer, Bjrn Pasternak, principal researcher at the Department of Medicine at Karolinska Institutet, said in a statement in the press release
