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The American diabetes association guidelines (2023) and the Chinese guidelines for the prevention and treatment of type 2 diabetes (2020) recommend that among people with type 2 diabetes who have established atherosclerotic cardiovascular disease or established kidney disease, a SGLT-2i or GLP-1RA with demonstrated cardiovascular disease benefit is recommended as part of the comprehensive cardiovascular risk reduction and/or glucose-lowering regimens

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Accurate diagnosis ensures appropriate management and excludes more serious underlying conditions

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Rare but potentially critical manifestations of overdose are cardiac arrest, chest pain, cardiac dysrhythmias, severe hypotension, seizures, and neuroleptic malignant syndrome