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Identifying and understanding rare side effects like dysesthesia and allodynia is part of the ongoing process of optimizing patient care with these powerful medications

In the DURATION 1 trial, after week 30, 130 patients with T2D who had been randomised to exenatide twice daily 10 g were switched to exenatide ER 2.0 mg

These GLP-1 agonists are in high demand by patients

Over the two-year study period, patients receiving GLP-1based therapy experienced: Importantly, the study authors did not observe an increased risk for key diabetes-related complications, including diabetic ketoacidosis and hypoglycemia

Adverse outcomes among participants with pre-existing SUDs included SUD related emergency department visits, SUD related hospital admissions, and SUD related mortality, and drug overdose and suicidal ideation or attempt