glp jdc-1 INVENTORY ADDITION: JDC1 STROBE GLP - JDC-1 | NRGSille
Description
Egan AG, Blind E, Dunder K, et al
doi: 10.1056/NEJMoa2028198
While GLP-1 receptor expression is absent in hepatocytes, GLP-1 receptor agonism exerts profound hepatic benefits through multiple indirect mechanisms
demonstrated that GLP-1 RAs could alleviate cytoplasmic Ca 2+ overload in VSMCs in SHRs, improve the arterioles systolic and diastolic functions, and reduce BPV by upregulating Na + /Ca 2+ exchanger 1 (NCX1) expression via the Akt signaling pathway [80]
Aim for 1.2 to 1.6 grams per kilogram of body weight per day
