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New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium

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Tirzepatide is a dual-agonist targeting GLP-1 and GIP receptors, while retatrutide is a triple-agonist that also activates the glucagon receptor

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Tirzepatide, a dual GIP/GLP-1 agonist, became the first FDA-approved medication for moderate to severe obstructive sleep apnea in adults with obesity

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It will typically stabilize after the first few weeks as the body adapts to the new metabolic baseline

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