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New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium

Tirzepatide is a dual-agonist targeting GLP-1 and GIP receptors, while retatrutide is a triple-agonist that also activates the glucagon receptor

Tirzepatide, a dual GIP/GLP-1 agonist, became the first FDA-approved medication for moderate to severe obstructive sleep apnea in adults with obesity

It will typically stabilize after the first few weeks as the body adapts to the new metabolic baseline
