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[DOI] [PubMed] [Google Scholar] 21.Mack CM, Soares CJ, Wilson JK, Athanacio JR, Turek VF, Trevaskis JL, et al

Moreover, it is increasingly recognized that weight loss itself primarily serves as a surrogate marker for favorable changes in body fat distribution, particularly reductions in ectopic fat depots such as visceral adipose tissue and intrahepatic lipid content, both of which are strongly associated with ASCVD risk (80, 81)

Those who took a placebo lost just 2.3% of their body weight

This is the stage almost nobody builds properly and is one of the major reason for the off-ramp
The FDA has received reports of adverse events, including hospitalizations, associated with compounded injectable semaglutide tied to dosing errors
