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It is estimated that GLP-1 released into the bloodstream contains 80% in the GLP-1 (736 amide) form and the remaining 20% is in the GLP-1 (737) form

Understanding what clinical research shows (and what it doesnt show) is essential before making any changes to your treatment plan

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Thyroid Function Monitoring For patients established on levothyroxine, thyroid function tests (TSH and free T4) should be monitored according to standard protocols: Every 612 months once stable on an established dose 68 weeks after any dose adjustment 68 weeks after starting or changing the dose of Saxenda After significant weight loss or gain More frequently if symptoms of hypo- or hyperthyroidism develop Patients should report symptoms suggesting inadequate thyroid replacement (fatigue, cold intolerance, weight gain, constipation) or excessive replacement (palpitations, tremor, anxiety, heat intolerance, unintentional weight loss)

Surveys of patients on semaglutide and tirzepatide consistently report reduced interest in alcohol, with some describing a complete loss of desire to drink