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Orforglipron and tirzepatide are completely different molecules

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In other words, after decades of advising HF patients to avoid drinking to prevent fluid buildup, we now have to explain to selected patients who show no signs of fluid retention that they risk dehydration due to their diuretic (or diuretic-like) therapy beyond LDs (MRAs, SGLT2I, sacubitril)

Within three months on Mounjaro 10mg, things were moving again. The nausea was worse for me at first on Mounjaro than it ever was on Wegovy
