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While peptide drugs have a wide range of therapeutic applications, their relatively short half-life has been a challenge, attributed to poor metabolic stability and a fluid dynamic radius below the glomerular filtration limit of the kidneys

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Theres evidence that these drugs affect the gut-brain axis, he adds, which might influence motility in more complex ways, but the main culprit is delayed gastric emptying. The gut-brain axis is the information superhighway between your gut and your brain