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Semaglutide remodels pancreatic islet physiology in a diet-dependent manner To explore the mechanisms underlying semaglutide-mediated improvement of glucose tolerance in both dietary conditions, we examined the morphology of pancreatic islets of CD and LPD mice treated with semaglutide or vehicle

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Centrally administered low-dose PRL (0.1ug/h infusion) increased hypothalamus dopamine levels, decreased serum prolactin and improved insulin secretory capacity and sensitivity

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