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Protective Cardiovascular Effects of GLP-1 There are also GLP-1 receptors in the brain which help activate nitric oxide synthase, causing vasodilatation to control blood pressure 4

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[MUSIC PLAYING] KWONG: This episode was produced by Rachel Carlson and edited by Brent Baughman

Proof of principle for the synergistic interaction of these 2 systems also in males comes from data showing that GLP-1-estrogen conjugate applied peripherally or directly to the CNS has superior effects of body weight loss, fat mass, or food-motivated behavior suppression in males (41, 42)