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Thus, all current evidence points to the suppression of energy intake being the underlying mechanism responsible for the beneficial effects of GLP-1R agonists on body weight in patients with obesity and/or T2D
This doesn't necessarily mean they're unsafeit means you may need to plan ahead or adjust dosing schedules with guidance from your healthcare provider or pharmacist

Patients with high-response GLP1R variants may feel significant appetite suppression even with minor timing shifts, so consistent scheduling becomes even more valuable
