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Lower healthcare utilization from obesity-related complications provides additional savings

Orlistat (Alli, Xenical) works by blocking fat absorption and predictably causes fatty, loose stoolsmaking it unsuitable for patients seeking to avoid diarrhea

70 No effects on risk were noted for semaglutide, lixisenatide, exenatide, nor albiglutide in which relative risks were not significant

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Since 503B facilities are required to report product lists and adverse events, they cannot claim these mandatory reports constitute development of information sufficient to trigger the Safe Harbor
