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p = 0.041) but not pancreatitis or pancreatic cancer was reported for GLP-1RAs compared with comparator treatments [59]

I believe these medications have such broad effects because a lot of health problems begin with disruptions in insulin resistance [abnormalities in how the body handles glucose] and inflammation, says Jamy Ard, MD, a professor of epidemiology and prevention at Wake Forest University School of Medicine in Winston-Salem, North Carolina

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Linagliptin in combination with metformin ameliorates diabetic osteoporosis through modulating bmp-2 and sclerostin in the high-fat diet fed C57BL/6 mice