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Well, if you look carefully, it doesnt really show any benefit to semaglutide either

GLP-1 Drug Prescriptions Have Doubled in Recent Years, But Many Users Quit Soon After Starting Use of Ozempic, Wegovy, Mounjaro and other GLP-1 drugs has spiked in recent years due to their effectiveness promoting weight loss, but side effects often cause users to discontinue the treatment within the first year

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It can also induce the placebo effect, with participants in those two groups saying that the supplement reduced cravings and less emotional eating. Lifevantage also did an in-vitro study on their Mindbody GLP-1 system, which showed a 150% increase in GLP-1 production

[38] performed automated oscillometric BP measurements and a finger photoplethysmography during the intravenous administration of placebo (saline 0.9%), exenatide, or a combination of exenatide and the nitric oxide-synthase inhibitor (L-NMMA) in 10 healthy overweight males