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A similar investigation was conducted in the US over a comparable timeframe, encompassing a larger cohort of diabetic patients

administration of the glycolysis inhibitor 2-deoxyglucose (2-DG) likewise increases activity of AMPK and blunts food intake suppression by i.c.v.-injected exendin-4 [714]

Melissa Taylor: writing original draft (equal), writing review and editing (equal)

GLP-1 agonists demonstrate potential beyond metabolic benefits, targeting inflammatory mechanisms underlying ulcerative colitis through pathways observed in preclinical research. For overweight patients with ulcerative colitis, these medications offer dual benefits: reducing inflammation while facilitating weight loss , which itself may decrease disease activity