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ActRII inhibition plus GLP-1 receptor agonism further decreases adipose tissue mass during weight loss To evaluate the effect of bimagrumab and semaglutide treatment on white adipose tissue (WAT) depots, we isolated and weighed inguinal (iWAT), epididymal (eWAT), retroperitoneal (rpWAT), and brown adipose tissue (BAT) depots at 14 days

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In the initial phase of treatment, dosing is typically introduced at lower levels to allow for physiological adaptation

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