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Reconstituted retatrutide should be refrigerated at 28 C and used within approximately 46 weeks

Rotating injection sites each week helps reduce skin irritation and improves medication absorption

While no food destroys GLP-1, certain foods can impair its effectiveness, such as: Refined sugars and simple carbohydrates Ultra-low-fiber diets Skipping protein regularly These foods can disrupt blood sugar, gut health and hormonal signaling

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The effect of early response to GLP-1 RA therapy on long-term adherence and persistence among type 2 diabetes patients in the United States