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[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Uhl P, Bajraktari-Sylejmani G, Witzigmann D, Bay C, Zimmermann S, Burhenne J, et al

A critical evidentiary hearing is set for May 14, 2025, where U.S

The review notes, however, that the degree to which these benefits are independent of weight loss may vary by condition, and further research is needed to elucidate these mechanisms fully

Introduced around the 2000s, these drugs have opened new avenues in weight management strategies, heralding a paradigm shift in obesity treatment

71 SURPASS-3 (ClinicalTrials.gov identifier: NCT03882970): assesses efficacy and safety of tirzepatide versus insulin degludec in patients with T2D prescribed metformin with or without SGLT2 inhibitors