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Diabetic patients on Mounjaro see roughly 12 to 15 percent body weight loss along with strong glycemic control

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Treatment generally starts with a lower dose to minimize side effects, gradually increasing to a therapeutic dose over several weeks

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For example, GLP-1 enhances L-type Ca 2+ currents through activation of the cAMP-dependent PKA pathway in canine cardiomyocytes [71], whereas when rat hippocampal neurons are pre-incubated with GLP-1 for 24 h, Ca 2+ currents are significantly decreased [58]