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The anti-inflammatory and antioxidant effects of GLP-1RAs observed in other organ systems may prevent damage in ocular tissues, leading to reduced risk of nonexudative age-related macular degeneration (AMD), exudative AMD, and primary open-angle glaucoma (POAG) compared to other diabetic medications (Figure 1)

Signs that levothyroxine dose adjustment may be needed include symptoms of hyperthyroidism (anxiety, palpitations, tremor, heat intolerance) or worsening hypothyroidism (fatigue, cold intolerance, weight gain despite GLP-1 use)

ELIXA [51] stato uno studio randomizzato, in doppio cieco, a gruppi paralleli disegnato per valutare limpatto di lixisenatide sul rischio cardiovascolare rispetto a placebo su una popolazione di 6068 soggetti adulti diabetici con recente episodio di sindrome coronarica acuta