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We recognized the need for a user-friendly and supportive platform where individuals could receive medically supervised care tailored precisely to their unique needs and health profile

Baseline estimated renal function was normal (eGFR 90 mL/min/1.73m2) in 57.2%, mildly impaired (eGFR 60 to 90 mL/min/1.73m2) in 35.9% and moderately impaired (eGFR 30 to 60 mL/min/1.73m2) in 6.9% of patients

However, Zepbound's gastrointestinal effectsincluding constipation in 16-17% and diarrhea in 18-24% of patientsmay indirectly increase hemorrhoid risk through straining or anal irritation

We believe the magnitude of weight loss, robust reductions in triglycerides, LDL (low-density lipoprotein) cholesterol and blood pressure, together with the safety profile observed in this trial, could potentially differentiate pemvidutide from the other incretin-based therapies, said Vipin K

Large meals will cause discomfort and take much longer to digest