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If your fatigue is not improving on the expected timeline, that is not a reason to push through silently

IL-1 is known to disrupt long-term potentiation and synaptic transmission [34] while TNF- alters postsynaptic AMPA receptor regulation [35], thereby impairing synaptic homeostasis

Several studies further reported reduced hospitalization rates and/or fewer cardiac events following ET in this population [79, 80]

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