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This third mechanism introduces direct hepatic fat mobilization, increased thermogenesis through brown adipose tissue activation, and accelerated peripheral lipid oxidation

The mechanism of action involves slowing gastric emptying, reducing appetite, and increasing feelings of fullness after eating

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Furthermore, central injection of GLP-1R agonists resulted in WAT browning

Additionally, optimizing access and equity in pharmacotherapy, as well as integrating these treatments into comprehensive care models, are critical areas for future investigation