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Description
For ingredient buyers, this change is already appearing in procurement, and demand for related ingredients is rising

That is actually good news
The new label includes references to some of those postmarketing risks, including intestinal obstruction, [and] severe constipation including fecal impaction. Some patients who took Zepbound have filed lawsuits, accusing Eli Lilly of failing to properly warn them that Zepbound could increase their risk of severe gut problems, including bowel obstructions, pancreatitis, and gastroparesis

It activates GLP-1 receptors located in the pancreas, brain, and digestive system

The trade-off between greater efficacy and increased side effect burden is real
