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MG1363-pMG36e-GLP-1 decreased the escape latency in mice that are injected with LPS

The participants were divided into two groups: insulin and exenatide

While the exact mechanisms remain incompletely understood, type 2 diabetes mellitus (T2DM) is strongly linked to the pathogenesis of AD ( At the molecular level, central or peripheral insulin resistance can result from reduced insulin receptor expression, decreased binding affinity, and disruption of downstream signaling pathways ( The ratio of serine-phosphorylated IRS to total IRS is widely used as a biomarker of insulin resistance in both brain and peripheral tissues