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Voluntary wheel running, a well-validated proxy for exercise in rodents, provides a robust framework to evaluate GLP-1R agonist effects on physical activity, as it is intrinsically rewarding and engages neural systems regulating motivation and energy expenditure (Greenwood et al., 2011
La frquence cardiaque et la pression artrielle doivent tre surveilles lors de chaque visite mdicale (au moins tous les 6 mois) dans le cadre de la routine clinique
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