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Incretin action of GIP is dramatically reduced in the presence of diabetes, as demonstrated by the evidence that glucose-dependent insulin secretion is not potentiated by GIP administration in subjects with diabetes [33, 34]

In the future, innovation may focus on five key areas: long-acting formulations, oral delivery methods, multi-target combination therapies, and expanding the range of indications

Los agonistas del receptor de GLP-1 son anlogos de incretinas que promueven la liberacin de insulina mediada por glucosa y se utilizan para tratar la diabetes tipo 2 y la obesidad

Managing side effects is key to sticking with treatment