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Description
At randomization, the initial insulin glargine dose in patients with HbA1c 8.0% was reduced by 20%
This resistance is primarily driven by increased oxidative stress, and desensitization of the sGCcGMPPKG signaling cascade [34]
Side effects at this dose People who tolerated 2.5 mg well usually handle 5 mg without major issues
These approaches address the potential underlying mechanisms discussed previously and can be implemented alongside continued medication use, following discussion with your healthcare team
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