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They tend to get full faster and eat less during meals

Limited Long-term Data : While short- to medium-term data are compelling, the long-term safety and efficacy profile over decades of treatment remains incompletely characterized

GLP-1 RAs are recommended to improve glycemia when there is a compelling need to minimize hypoglycemia and/or minimize weight gain or promote weight loss

Common Side Effects and Safety Considerations Gastrointestinal side effects are the most frequently reported adverse reactions with GLP-1 receptor agonists, affecting a substantial proportion of patients, particularly during treatment initiation

Within the black box, the FDA explains that the medications cause rodents to develop thyroid C-cell tumors, but that it is unknown whether the same occurs in humans